Brain natriuretic peptides (BNP) are produced initially as a 134 amino acid pre-pro-peptide, which is cleaved into proBNP as 108 amino acids. This precursor molecule is stored in secretary granules in myocytes. Upon release, proBNP is cleaved by a protease into N-terminal (NT)-proBNP (a 76 amino acid, biologically-inert portion), and BNP (which is biologically active). The highest concentrations of NT-proBNP and BNP are found in the left ventricular (LV) myocardium, but are also detectable in arterial tissue and the myocardium of the right ventricle. A significant body of evidence has developed to demonstrate that NT-proBNP and BNP levels correlate with diagnosis, clinical status, and prognosis in congestive heart failure (CHF).

Technology: Immunochromatography
Turn Around Time: 15 minutes
Sample Type: Whole Blood, Plasma, or Serum
Volume of Sample Required: 80 μl

Measuring Range: 30 pg/mL- 15,000 pg/mL

Shelf Life: 15 months
Package: 20 test cassettes / box
Box Contents: 20 test cassettes, 20 micro pipettes, 1 instruction manual